V.1(1) 8. Original Research: FORMULATION & COMPARATIVE EVALUATION OF POLYHERBAL PREPARATIONS FOR THEIR DISINFECTANT EFFECTS

Zeeshan Afsar1*, Salma Khanam2, Syed Aamir3

1Department of Pharmacognosy, Farooqia College of Pharmacy, Rajiv Gandhi University of Health Sciences, Mysore, Karnataka, India.

2Department of Pharmacognosy, AlAmeen College of Pharmacy, Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India.

3 Department of Pharmacology, Farooqia College of Pharmacy, Rajiv Gandhi University of Health Sciences, Mysore, Karnataka, India.

ABSTRACT

Background: The essential oils and extracts from several plant species can be used for their disinfectant properties for eliminating microorganisms related to skin, dental caries and food spoilage, including gram-negative and gram-positive bacteria, fungi and viruses.

Objective:  To test different prepared formulations for the comparative disinfectant efficacy.

Methodology: The leaf and bark extracts of the plants Cassia fistula, Ficus religiosa, Milletia pinnata and Wendlandia thyrsoidea were subjected to antimicrobial screening. The extracts that exhibited maximum antimicrobial effect were used to prepare the cream, gel, hand wash, sanitizer and soap formulations. The prepared formulations were tested for their disinfectant efficacy by various methods such as Hand wash method, Degerming method, Ditch plate method and Rideal Walker coefficient methods.

Results: Results showed that all the formulations exhibited significant disinfectant properties among which the sanitizer and soap exhibited maximum disinfectant effect which was comparable with the commercially available market preparations.

Conclusions: The study concluded that plant extracts exhibits good antimicrobial activity and the prepared formulations exhibited good disinfectant efficacy, as well when evaluated by various disinfectant testing methods.

Keywords: Polyherbal preparations, disinfectant, comparative evaluation, Formulation
 *Corresponding author email: zeeshanafsar@gmail.com

This is an open access article under the CCBY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

CITE:
Afsar Z, Khanam S, Aamir S. Formulation and Comparative Evaluation of Polyherbal Preparations for Their Disinfectant Effects, The International Journal of Therapeutics  2018; 1(1):54-65.

© 2018 Publishing services provided by The International Journal of Therapeutics (IJTHERA) Website: https://www.ijthera.com 


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